Author(s)
Gitanjali Shivaji Bhatjire, Dr. Bhavesh Akbari, Dr. Vasim T Pathan, Dr. Atul R. Bendale, Dr. Anil G. Jadhav
- Manuscript ID: 140064
- Volume: 2
- Issue: 2
- Pages: 31–46
Subject Area: Pharmaceutical Science and Pharmacology
Abstract
Liposomes are versatile nanocarrier vesicles, composed of Phospholipids, featuring both a hydrophilic core and hydrophobic membrane. This dual nature makes them ideal for delivering molecules with varying polarities. Their biocompatibility, biodegradability, and ability to target specific tissues have established them as a cornerstone in anticancer drug delivery system. Today, liposomes are actively used in tumor targeting, gene therapy, genetic vaccines, immunomodulation, photodynamic therapy, transdermal delivery. In the oncology sector, these nanovesicle formulations depict a significant advancement by offering innovative solutions for the delivery of chemotherapeutic agents. This article confronts latest developments in widely used liposome formulation methods including thin film hydration method, Solvent evaporation, microfluidic techniques. Each method presents distinct advantages, challenges and limitations, which are discussed in detail. Additionally, the review highlights advanced approaches and future directions in the field of liposomal drug delivery.