Author(s)
Viraj Arun Daunge , Sahil deshmukh, Bhakti dhage, Vandana shirsath
- Manuscript ID: 140096
- Volume: 2
- Issue: 1
- Pages: 138–157
Subject Area: Medicine and Healthcare
Abstract
This review provides a comprehensive comparative analysis of several novel drug delivery systems (NDDS), highlighting their applications across diverse diseases. Emphasis is placed on the latest advancements in nanoparticulate delivery platforms—including liposomes, tocosomes, hydrogels, microneedles, and nanobots—and their ability to overcome limitations of conventional dosage forms. The discussion encompasses critical aspects such as targeted drug delivery, controlled release, improved drug stability, and biocompatibility. NDDS technologies are shown to optimize therapeutic efficacy while minimizing toxicity, promote personalized and regenerative medicine, and facilitate advanced diagnostic and therapeutic methods. The challenges of poor bioavailability, rapid clearance, and limited biological distribution are addressed through engineering strategies, with particular focus on carrier types and their respective advantages and disadvantages. The review synthesizes current clinical evidence, recent drug examples, and ongoing translational challenges, positioning NDDS as pivotal drivers in modern medical treatments