Author(s)
Om Sandeep Shelke , Poonam Manoj Yadav
- Manuscript ID: 140287
- Volume: 2
- Issue: 6
- Pages: 345–367
Subject Area: Other
Abstract
The main aim to present work is to formulate and evaluate poly-herbal hand wash by using aloe-vera, Sandal wood. In order to make formulation has less side effects and better cleaning of hands. The hands are primary sites for the infection. Microbial infection is critical Issue in children and employer in pharmaceutical industry. So the use of hand wash is more in industrial site The formulated hand wash hence found to be good in physical parameter with good cleaning of hands. Therefore, it brings up the use of antiseptic for hand washing purpose. The prepared Handwash evaluated by the different parameter namely as colour, Odour, ph, viscosity and stability. The numerous of antiseptic hand wash available in the market are alcohol based sanitizers which have some adverse effects. To avoid these adverse effects like itching, drying, irritation, dermatitis etc., of the synthetic Handwash formulations an attempt has been made to formulate a Polyherbal hand wash using extracts of ginger rhizomes extracts. The anti-microbial activity of prepared poly-herbal hand wash was tested against skin pathogens collected from volunteers, and its efficiency was verified using Cup Plate Method. The results from Cup Plate Method showed that hand wash prepared from alcoholic extract of ginger rhizomes and aqueous extract of ginger rhizomes have effective activity due to combined activity of phytoconstituents present in extracts. The results from the present work support the incorporation and utilization of herbs in formulations to give a better effect. Herbal hand wash evaluated by tested parameters like physical parameters like colour, fragrance and chemical parameters like pH, Viscosity, Foam height, Foam retention, Anti-Microbial Activity, Skin irritation test etc. and obtained results were in the acceptable limits with less or no side effects. Two formulations of Handwash were prepared and the formulations were evaluated for physical properties like appearance, pH and viscosity. The antimicrobial activity of prepared formulations of hand wash was checked against skin pathogens Bacillus subtilus, Staphylococcus, Pseudomonas aeruginosa and Escherichia coli by agar diffusion method. The aim of present work was to prepare formulations of poyherbal handwash from the ethanolic extracts of ginger rhizomes.